Thursday 26 January 2023, 15:30-17:00 Berlin time (14:30-16:00 London time)
Video | Transcript ENG | Transcript GER
Slides: Introduction to the problem in Germany | A possible solution for Germany
The UK is the first country worldwide to set up a watertight national system that will ensure that all interventional clinical trials are pre-registered and make their results public. In future, the UK ethics regulator will directly register all trials immediately after they receive ethics approval, and will later check whether their results were made public, ending research waste once and for all. Quick overview of the UK model here.
In many other countries, there has been significant progress in curbing medical research waste in recent years, but that progress has largely been limited to the minority of clinical trials that are subject to legal reporting requirements. For most other trials, the problem continues unchecked. For example, a recent study of German university trials found that 29% had never made their results public, wasting public money, slowing down scientific progress, and undermining public health.
This live discussion organised by the TranspariMED campaign is bringing together some of the key players involved in developing the UK’s pioneering system to discuss with experts from other countries how this model could be applied to other jurisdictions, with a particular focus on Germany.
All attendees are strongly encouraged to contribute questions and comments during the debate.
Marc Taylor:
In 2011-2022, Marc Taylor chaired the not-for-profit company which owns the ISRCTN registry of clinical research. ISRCTN, based in the UK, is a primary registry in the World Health Organization's system of clinical trial registries.
Before leaving government service in 2011, Marc was one of a team of British officials who established the National Institute for Health Research and related systems, including the Health Research Authority, to enable high quality health research in England.
In earlier roles in government, he was responsible for finance policy development and budgets in health care and overseas development assistance.
Christoph Stein:
Christoph Stein studied Medicine at Ludwig-Maximilians-University (LMU) München, Germany, and underwent specialty training in Anesthesiology, Pain Medicine and Neuropharmacology at State University of New York, University of California Los Angeles, LMU and Max-Planck Society. From 1992-97 he served as Professor at Johns Hopkins University and the National Institute on Drug Abuse (Baltimore, USA). In 1997 he assumed the Chair of Anaesthesiology and Intensive Care Medicine at Freie Universität Berlin, Germany (since 2003: Charité Campus Benjamin Franklin). He is a board member of TI-D and represents its working groups on Science and Health Care.
Valerie Labonte:
Valerie is originally a biologist and is now working as a scientific staff member at Cochrane Germany and the Institute for Evidence in Medicine at the university clinic Freiburg, Germany. Besides working on evidence synthesis, Valerie is part of Cochrane Germany’s advocacy team, currently working on trial transparency.